產品屬性：
產品名稱 | AR420626 |
規格 | 500μg、1mg、5mg、10mg |
貨號 | EY-01Y17631 |
Cas No.: 1798310-55-0
別名: N/A
化學名: N-(2,5-dichlorophenyl)-4-(2-furanyl)-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-3-quinolinecarboxamide
分子式: C21H18Cl2N2O3
分子量: 417.3
溶解度: 5mg/mL in DMSO, 2mg/mL in DMF
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Free fatty acid receptor 3 (FFAR3; GPR41) is a G protein-coupled receptor activated by short chain fatty acids (SCFAs). It is expressed in adipose tissue, the gastrointestinal tract, and the peripheral nervous system, and it is involved in SCFA-dependent energy regulation.[1] AR420626 is a selective agonist of FFAR3 (GPR41; IC50 = 117 nM) that does not activate the related receptor FFAR2 (GPR43) at concentrations up to 100 μM.[2] At 10 μM, it can stimulate a 1.26-fold increased release of glucagon-like peptide-1 from colonic crypt cultures.[3]
特別提醒公司產品僅供科研使用
