產品屬性：
產品名稱 | ACT 462206 |
規格 | 10 mg、50 mg |
貨號 | EY-01Y17895 |
Cas No.: 1361321-96-1
別名: N/A
化學名: N/A
分子式: C20H24N2O4S
分子量: 388.48
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Potent, dual orexin receptor antagonist (IC50 values are 11 and 60 nM for OX2 and OX1 receptors respectively). Exhibits anxiolytic-like properties in vivo. Brain penetrant.Boss et al (2014) Structure-activity relationship, biological, and pharmacological characterization of the proline sulfonamide ACT-462206: a potent, brain-penetrant dual orexin 1/orexin 2 receptor antagonist. ChemMedChem. 9 2486 PMID:25147058
特別提醒公司產品僅供科研使用
