產品屬性：
產品名稱 | Chrodrimanin B |
規格 | 1mg |
貨號 | EY-01Y17963 |
Cas No.: 132196-54-4
別名: N/A
化學名: N/A
分子式: C27H32O8
分子量: 484.5
溶解度: DMSO: Soluble,Ethanol: 1 mg/ml,Methanol: Soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Chrodrimanin B is a meroterpenoid fungal metabolite that has been found in Talaromyces species.1 It has insecticidal activity against third instar silkworm larvae (LD50 = 10 μg/g of diet). Chrodrimanin B selectively inhibits the silkworm GABA receptor RDL (IC50 = 1.13 nM) over human α1β2γ2 subunit-containing GABA receptors (IC50 = 1.48 μM).2 The structure of thailandolide B, originally described as a C-9 epimer of chrodrimanin B, was revised in 2012 and is identical to that of chrodrimanin B.1References1. Hayashi, H., Oka, Y., Kai, K., et al. A new meroterpenoid, chrodrimanin C, from YO-2 of Talaromyces sp. Biosci. Biotech. Biochem. 76(4), 745-748 (2012).2. Xu, Y., Furutani, S., Ihara, M., et al. Meroterpenoid chrodrimanins are selective and potent blockers of insect GABA-gated chloride channels. PLoS One 10(4), e0122629 (2015).
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