產品屬性：
產品名稱 | Acetylthiocholine (iodide) |
規格 | 5 g、10 g、25 g、50 g |
貨號 | EY-01Y17971 |
Cas No.: 1866-15-5
別名: N/A
化學名: N/A
分子式: C7H16NOS·I
分子量: 289.2
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Acetylthiocholine is a substrate for acetylcholinesterase (AChE) and an agonist of α4β2 subunit-containing nicotinic acetylcholine receptors (nAChRs).1,2 It binds to α4β2 subunit-containing nAChRs in SH-EP1 cells (IC50 = 7.1 μM for the human receptor) and induces rubidium efflux in an agonist-induced rubidium efflux assay (EC50 = 100 μM).2 Acetylthiocholine has been used as part of a thiocholine sensor for the detection of pesticides in complex sample types, such as soil, groundwater, and spinach.1 1.Chen, L., Tian, X., Li, Y., et al.Broad-spectrum pesticide screening by multiple cholinesterases and thiocholine sensors assembled high-throughput optical array systemJ. Hazard. Mater.402123830(2021)
2.Eaton, J.B., Peng, J.-H., Schroeder, K.M., et al.Characterization of human α4β2-nicotinic acetylcholine receptors stably and heterologously expressed in native nicotinic receptor-null SH-EP1 human epithelial cellsMol. Pharmacol.64(6)1283-1294(2003)
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