產品屬性：
產品名稱 | Steviol |
規格 | 5mg、10mg、25mg、50mg |
貨號 | EY-01Y20027 |
Cas No.: 471-80-7
別名: N/A
化學名: N/A
分子式: C20H30O3
分子量: 318.5
溶解度: DMF: 30 mg/mL,DMSO: 25 mg/mL,Ethanol: 30 mg/mL,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL
儲存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from S. rebaudiana. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. It is selective for hOAT1 and hOAT3 over hOAT2 and hOAT4 (IC50s = 11.4, 36.5, 1,000, and 285 μM, respectively). Uptake assays in mouse renal cortical slices yield similar results with IC50 values of 12.8 and 67.6 μM for hOAT1 and hOAT3, respectively. Due to the use of steviol glycosides as sweeteners, the safety of steviol is widely studied, including its genotoxicity and toxicokinetics.
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